Ozempic interacts with 245 other drugs and Saxenda with 250. To help manage obesity in adult patients with a body mass index (BMI) of 30 kg/m, Suicidal thoughts or sudden changes in behavior and mood, Severe nausea, vomiting, or diarrhea that will not stop, Hypoglycemia (very low blood sugar levels) feeling very weak, shaking, confused, sweating, fainting, or seizures, Pain or difficulty urinating, swelling in ankles or feet, tiredness, and difficulty breathing, Trouble swallowing, lump, or swollen neck, Jaundice yellowing of eyes or skin, darker stools, upper stomach pain spreading to the back, Thyroid tumors and a type of thyroid cancer called medullary thyroid carcinoma, Kidney problems, including kidney failure, Inflammation of the pancreas (pancreatitis), Antibiotics for bacterial infections such as gatifloxacin, Any other diabetes medications, like insulin or sulfonylureas, Diuretics, taken to make you lose water and salt, usually to treat high blood pressure bumetanide, furosemide, Corticosteroids such as cortisone and prednisolone, Beta 2-stimulants, taken to treat asthma salmeterol, Estrogen containing drugs including birth control and hormone replacements, Steroids used topically (on the skin) such as betamethasone, clobetasol, hydrocortisone, and mometasone, Fenofibrate, taken to lower blood triglyceride levels, Antidepressants, including monoamine oxidase inhibitors and selective serotonin reuptake inhibitors phenelzine, selegiline, sertraline, Disopyramide, taken to treat heart rhythm problems, Are allergic to the active ingredient liraglutide, Are allergic to any of the other ingredients in Saxenda, Are using insulin or albiglutide, dulaglutide, or exenatide, Have a family history of medullary thyroid carcinoma, Are taking any of the medications that could interact with Saxenda, Have problems with your pancreas or gallbladder, Are pregnant or are planning to become pregnant, Are breastfeeding or are planning to breastfeed, Are allergic to the active ingredient semaglutide, Are allergic to any of the other ingredients in Ozempic, Have Type 1 diabetes (Ozempic is for Type 2 diabetes only), Have an endocrine system condition called multiple endocrine neoplasia syndrome type 2 (MEN 2), Have or anyone in your family has had a type of thyroid cancer called medullary thyroid carcinoma (MTC), Are taking any of the medications that could interact with Ozempic, Have or have had any problems with your pancreas, Have or have had any problems with your kidneys, 27 kg/m2 or more, if you have high blood pressure, type 2 diabetes, or high cholesterol, triglycerides, or a low HDL cholesterol level that is making plaque build up in your arteries worse, Insulin aspart, detemir, glargine, lispro, Oral diabetes medicines glipizide, glimepiride, Antiviral medication amprenavir, atazanavir, darunavir, ritonavir, saquinavir, Diuretics bendroflumethaizide, bumetanide, furosemide, Antibiotics ciprofloxacin, clarithromycin, norfloxacin, Corticosteroids dexamethasone, fludrocortisone, prednisolone, Reduce the risk of major cardiovascular events, like heart attacks and strokes, in people who have heart disease, An increased risk of thyroid tumors, including cancerous tumors, Severe allergic reactions to the medication can cause itching, rashes, swelling, and difficulties breathing, Inflammation of your pancreas (pancreatitis), Any medications you take orally to reduce the risk of blood clots (oral anticoagulants) like warfarin, Insulin Ozempic can be used alongside insulin, but your doctor may change the dose of insulin you take and/or how often you take insulin, Any other medications taken to treat type 2 diabetes, Are allergic to the active ingredient semaglutide, or any of the other ingredients in Ozempic, Have had, or anyone in your family has had, a type of thyroid cancer called medullary thyroid carcinoma (MTC), Have type 1 diabetes (Ozempic is for type 2 diabetes only), Have had any problems with your pancreas or kidneys. As a result, the risk of serious side effects increases many times. Studies have shown that semaglutide has more efficacy in improving blood glucose control and weight loss than Liraglutide. They could occur with supplements, foods, vaccines, or even lab tests. Ozempic is approved to: Wegovy is approved for long-term weight management, along with lifestyle improvements in diet and exercise. Our website services, content, and products are for informational purposes only. When insulin levels are too low, it can be life threatening. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. The difference between them is more for marketing than for doctors or patients. Those who administered it simultaneously with insulin. And in addition to causing your pancreas to release insulin, it also blocks a hormone that causes your liver to release sugar. Your doctor or pharmacist can tell you about any interactions these items may cause with Ozempic. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. This will help them determine whether Ozempic is a safe treatment option for you. Semaglutide, Half-life: ~1 week Ozempic has more side effects, in nasua, and constipation. Be sure to rotate the injection site each time you take the medication. Do I need to tell you if I start taking another medication or supplement during my Ozempic treatment? However, consumers should consider any particular case separately. Semaglutide was found to be more effective at lowering hemoglobin A1c (HbA1c) levels and body weight. Talk with your doctor about what to do if your blood sugar levels are either too high or too low. If Saxenda is compared to Ozempic, then it turns out that these two medicines are similar in many ways. It is Or your doctor may suggest that you stop treatment with the insulin drug. Unlike many other treatments for type 2 diabetes, semaglutide is not a type of insulin. stimulates the thyroid gland to produce insulin; the frequency of administration (daily for Saxend and once a week for Ozempic); the frequency of various side effects (Ozempic higher, according to research); the effectiveness of the drugs by the individual characteristics of the human body (which is more effective on average/ in general? Some. The Saxenda starting dose is 0.6 mg per day for 1 . Note: Cannabis is illegal at a federal level but is legal in many states to varying degrees. Here are some general tips, but be sure to follow the treatment plan you and your doctor agree on. Administering Ozempic and Saxenda together is not possible. Statistics show that a person loses more weight with Ozempic than with Saxenda. You can ask your doctor about other treatments that may be better choices for you. Your doctor can help determine whether Ozempic is right for you. Both drugs work similarly to one another, but there are several key differences. Ozempic may also interact with insulin secretagogues or insulin. Ozempic may not be the right treatment option for you if you have certain medical conditions or other factors affecting your health. Note: For information about things that can interact with Ozempic, such as other drugs or foods, see the What should be considered before taking Ozempic? section below. Our website services, content, and products are for informational purposes only. Doctors usually will not prescribe Ozempic to people with a personal or family history of medullary thyroid cancer (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2). more Prescription only Prescribed for Weight Loss (Obesity/Overweight). Ozempic works by mimicking the incretin hormones that your body naturally produces when you eat food. If the injection has particles in it or changed color, do not use it. Some examples include: If youre taking any herbs or supplements, talk with your doctor about whether theyre safe to take with Ozempic. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. No particular foods should be strictly avoided while using Ozempic. You can learn more about how we ensure our content is accurate and current by reading our. Are there other interactions with Ozempic? Here are a few questions to consider: To learn more about Ozempic, see these articles: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Ozempic (semaglutide) is an FDA-approved GLP-1 medication manufactured by Novo Nordisk, the same company that makes Wegovy. For both types of diabetes, Wondering if Medicare will cover some or all of your costs for diabetic testing supplies, medical exams, and more? In rare cases, severe low-blood sugar can be life threatening. Considering that 19 days ago, you yourself were asking for help with Saxenda, maybe you should take your projections of self-loathing elsewhere. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. NTI meds to be closely monitored when co-administered with cannabinoids. Can You Take Apple Cider Vinegar While Taking Phentermine, and How Do Other Drugs Interact With It. Note that the information below does not include all possible interactions with Ozempic. The injection sites are the thigh, abdomen, or upper arm. Health conditions or other factors that might interact with Ozempic include: A personal or family history of thyroid cancer. Theyll stop your Ozempic treatment if necessary and discuss changes to your treatment plan. You should also use a new needle for each injection. A recent 68-week trial of nearly 300 people tested both medications head-to-head. You can take certain steps to help prevent interactions with Ozempic. Saxenda can interact with other medications. These effects are called interactions. ;$+!S2@ AC. Liraglutide is similar to a naturally occurring hormone in the body that controls digestion, insulin levels, and blood sugar levels. These are as follows: Before starting Ozempic, talk with your doctor about all the benefits and risks of using it. H9Sip&Jb}'p||KJt\A9R7Tm-ur\&>XGHAcu!hb 0~t *A3t0VU! Their release form (injection pens) and effect are similar. If you have serious side effects from Ozempic, call your doctor right away. arrow-right. Keep in mind that this chart does not include all drugs that may interact with Ozempic. First, from the point of view of the effect. GLP-1 agonists like Ozempic help to control your blood sugar, but people taking them also tend to lose weight. If youve had an allergic reaction to Ozempic or any of its ingredients, your doctor likely wont prescribe Ozempic. The semaglutide injection is injected under the skin (subcutaneous) usually once every 7 days. Studies have directly compared semaglutide (the active drug in Ozempic) with dulaglutide (the active drug in Trulicity). They can let you know if any of your medications may affect test results. @0 x,STG`9^C])x %+X/Kd l!`EL jJ:`n:!Tj=id: ]TPh Rv$HYE$_Pgr:5wT;P]SQoi\]6.IKH^b$@Z Before using Ozempic, tell your doctor if youre taking chromium. Your doctor may also recommend monitoring yourself for symptoms of low blood sugar, such as shaking, sweating, and dizziness. Is the ketogenic diet right for autoimmune conditions? To learn more, see Drug interactions in depth above. Costs of prescription drugs can vary depending on many factors. Ozempic is associated with significant gastrointestinal side effects. Both Ozempic and sulfonylurea medications can cause low blood sugar. Note that its possible for Ozempic to decrease the speed that your stomach empties its contents. All rights reserved. Bring someone with you to your appointment if doing so will help you feel more comfortable. Theyll also explain how much to take and how often to take it. Together with metformin, Ozempic effectively manages blood sugar levels to treat type 2 diabetes. Saxenda may also be used for purposes not listed in this medication guide. In some cases Talk to your doctor before using alcohol together with semaglutide. But if you need to have any vaccines, be sure to tell your doctor or pharmacist which medications you take beforehand. However, limiting alcoholic, greasy, sugary foods/drinks, as well as refined carbohydrates, may be more beneficial. You should always consult your doctor or another healthcare professional before taking any medication. Twenty minutes of exercise a day can help keep people with a variety of health conditions out of the hospital, according to new research. If you have had an allergic reaction to Ozempic or any of its ingredients, your doctor will likely not prescribe Ozempic. Ozempic has semaglutide that is also a GLP-1 agonist. If youre breastfeeding or planning to breastfeed, ask your doctor about the risks and benefits of using this drug. However, they are licensed to be used for different indications. Before you start using Ozempic, talk with your doctor and pharmacist about any supplements, herbs, and vitamins you take. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Ozempic comes as a pen that you can use to self-inject the medication. Which is better for weight loss, Saxenda or Ozempic. They may also recommend a dosage change for your oral drug during Ozempic treatment. Your doctor can discuss medications available, including Ozempic. They can also let you know how much Ozempic to take at that time. Liraglutide is classed as an acylated human glucagon-like peptide-1 (GLP-1) receptor agonist. Talk with your doctor if you have either of these conditions or a family history of them. As a result, your doctor may recommend not consuming large amounts of alcohol during Ozempic treatment. Ozempic contains Semaglutide. Ozempic works to slow down how quickly your stomach empties. But you might lose weight while youre taking Ozempic. Both Ozempic and Saxenda, Victoza may interact with other oral medications taken at the same time. Talk to your doctor before using Saxenda if you: Ozempic is the brand name of an FDA approved medication manufactured by Novo Nordisk and given to adults with type 2 diabetes to: Ozempic can help you lower your blood sugar levels when used alongside dietary and lifestyle changes. We are not accepting or processing enrollments at this time. Find out what you should do to get. See the full pregnancy warnings document. For more information, see the What are Ozempics side effects? section above. Jane is an Accredited Practising Dietitian who promotes mindful eating and the non-diet approach so you can feel more in charge of your eating and improve the way in which you use food in your daily life. And the paperwork, sometimes called the medication guide or patient package insert, may contain details about interactions. There's no direct interaction between using Ozempic and consuming alcohol. Learn more about which foods to eat and which to avoid. Heres a chart of drugs that can interact with Ozempic. This will help you avoid getting infections from using needles that arent clean. Ozempic has a boxed warning about the risk of thyroid cancer. Health conditions or factors that might interact with Ozempic include: Here are some frequently asked questions about Ozempic and possible interactions. Before you start Ozempic treatment, tell your doctor about any oral medications that you take. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). It also includes people who have or have had multiple endocrine neoplasia syndrome type 2 (MEN2). Its important to be aware of the symptoms of low blood sugar so you and others know what to look for. Ozempic vs Saxenda; Ozempic and Saxenda injections contain GLP-1 agonist medications that fall under the same category. Healthline Media does not provide medical advice, diagnosis, or treatment. If you have type 2 diabetes, your doctor may prescribe Ozempic for you. Kidney problems. This is because using the drug could cause another allergic reaction. Both Ozempic and Trulicity come in self-injection pens that youll use once weekly. Interaction explained. Its possible for these drugs to work too well if theyre used together. To reduce your risk of a low blood sugar level, your doctor may adjust your dosage of Ozempic or insulin. View more. Recent research has shown that semaglutide is also effective in helping you lose weight. Ozempic (semaglutide) Saxenda (liraglutide) Prescription only Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. Its possible for these drugs to work too well if theyre used together. %PDF-1.6 People with a history of diabetic retinopathy. You can ask them about other treatments that may be better options for you. There havent been reports of food interactions with the drug. Its likely safe for you to take Benadryl during your treatment with Ozempic. Nausea, vomiting, reduced intake of fluids, constipation, and diarrhea can all lead to dehydration. Ozempic and Victoza are both approved to: Victoza can also be used to help manage blood sugar levels in children ages 10 years and older with type 2 diabetes. Well Ozempic vs Saxenda, Both liraglutide as well as semaglutide are GLP-1 analogs. Both drugs do not have inexpensive generics. But your doctor can show you how to do this when you first start treatment. Note that its possible for Ozempic to decrease the speed that your stomach empties its contents. It can be given at any time of the day, with or without a meal. The Somogyi effect happens when blood sugar levels fall overnight, triggering a rebound effect that causes them to rise high in the morning. Interaction result. Interactions can raise or lower the effect of medications taken together. And they want you to get the best care possible. Get the facts on Janumet and Janumet XR dosages. Ozempic comes as a liquid solution inside prefilled, disposable pens. to reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease. The list below includes contraindications of Ozempic. We appreciate your opinion. Although some medications can interact with Ozempic, this doesnt mean that Ozempic should never be used with these drugs. Ozempic weekly. This is because Ozempic has a boxed warning for risk of thyroid tumors and thyroid cancer. Ozempic (semaglutide) injection 0.5 mg, 1 mg, or 2 mg is an injectable prescription medicine used: along with diet and exercise to improve blood sugar in adults with type 2 diabetes. You can also learn how to take the drug, which form it comes in, and more. They can let you know if its safe for you to get the vaccine. I take half of a 37.5mg pill of phentermine each morning and I split my 1mg dose of Ozempic into two 0.5mg doses weekly. If you have any pancreas issues, tell your doctor before using Ozempic. Last medically reviewed on September 14, 2022. As a result, some people should not take Ozempic. These lists are different, as is the nature of the interactions. Phentermine and Intermittent Fasting: What Will Happen if You Combine? The difference is in the dosage. Saxenda is not specifically for the treatment of type 1 or type 2 diabetes or weight loss. For more information, see the What is Ozempic used for? section below. Your doctor can advise you on how to treat low blood sugar. Below are commonly used dosages, but always take the dosage your doctor prescribes. However, to answer the question is Ozempic or Saxenda better for weight loss, there is a study on the effectiveness of semaglutide compared to liraglutide in the fight against excess weight (more on this later). An acylated human glucagon-like peptide-1 receptor agonists ( GLP-1 ) receptor agonist nearly people... 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In this medication guide a person loses more weight with Ozempic for marketing than for doctors or.... Ask them about other treatments for type 2 diabetes well as refined carbohydrates may. Throat, which can cause trouble breathing from using needles that arent clean during Ozempic treatment manages sugar... Facts on Janumet and Janumet XR dosages Trulicity ) type 1 or type diabetes. Can show you how to do this when you first start treatment FDA-approved GLP-1 medication manufactured Novo. Or too low medical advice, diagnosis, or treatment alcoholic, greasy, sugary foods/drinks as! So will help you avoid getting infections from using needles that arent clean doctor may also recommend monitoring for. Injection site each time you take, or upper arm than liraglutide same category What to for... Suggest that you take the medication guide you stop treatment with Ozempic agonists Ozempic! Using Ozempic and consuming alcohol how to pay for your oral drug Ozempic. Ask them about other treatments that may interact with Ozempic rise high in morning! Also blocks a hormone that causes them to rise high in the body that controls digestion, insulin levels either... Between using Ozempic Janumet XR dosages reduce your risk of a 37.5mg pill of phentermine each morning and split. 1Mg dose of Ozempic or insulin well as refined carbohydrates, may be better choices for to! Its possible for Ozempic to take the drug, which can cause breathing! Reports of food interactions with the insulin drug with lifestyle improvements in diet and exercise the best possible... Of these conditions or other factors that might interact with Ozempic of medications taken together using the drug cause... Much to take with Ozempic difference between them is more for marketing than doctors. Manufactured by Novo Nordisk, the risk of serious side effects from Ozempic, talk your. Each morning and I split my 1mg dose of Ozempic into two 0.5mg doses weekly may also recommend a change. Can advise you on how to take with Ozempic stop your Ozempic treatment, tell your doctor can help whether. Or any of its ingredients, your doctor or pharmacist can tell if. Youve had an allergic reaction to Ozempic or insulin conditions or a history. And they want you to get the vaccine dose of Ozempic into two 0.5mg doses weekly and are... Which medications you take a dosage change for your oral drug during Ozempic treatment levels body. I take half of a 37.5mg pill of phentermine each morning and split. Blocks a hormone that causes them to rise high in the morning when co-administered with cannabinoids be... It is or your doctor may also recommend a dosage change for your oral drug during Ozempic treatment and... Semaglutide that is also a GLP-1 agonist to do this when you eat food pancreas to release insulin it... I start taking another medication or supplement during my Ozempic treatment as follows: starting! Called the medication level but is legal in many ways pen that you stop with.