estrogen primed microdose lupron flare protocol karelaestrogen primed microdose lupron flare protocol karela

Create an account to follow your favorite communities and start taking part in conversations. My first stim cycle was Antagonist and we actually did cancel ER. I think it helps with the 2ww. I am feeling dejected, as I have had 3 cycles in the last 6 months, in which I have ovulated early twice. And I wasnt pregnant. Thank you. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. Of the 11 eggs that fertilizedsuccessfully across the 3 cycles, we had 9 of them make it to blastocysts and got 4 chromosomally normal embryos. sometimes a bcp is used for this same purpose. Instead I'll have my blood checked for progesterone levels to see where I am in my cycle (since the cancelled IVF fucked that all up). My FSH is 6.5. The reason they had me on that protocol was because a) I generally respond GREAT to drugs, and b) my AFC is pretty fine and my age is "young-ish" so they think my low AMH will just mean to expect slightly fewer eggs that will be good quality. Called GnRH antagonists, these medications work differently than the GnRH agonists like Lupron. Clomid, 2 IUI cycles, and 5 IVF cycles = BFN, FET #1 August 2013 = BFP! What's weird is all of my levels are normal and i'm so young so i think the doctor and nurses are all perplexed as to how my egg quality was so bad! This is witho. For my IVF cycle I was on bcps for two weeks. When I stimmed, this is also the thickest I ever was. Curious to see if anyone has had success using the long lupron protocol with DOR? Seems like a, Protocols to thicken uterine lining after D&C and scarred tissue. The clinic I was with was horribly unorganized, I never saw my doctor, and dealing with insurance was a nightmare which made every, Looking for advice ---- Siggy warning ------ Me 34 y/o DH 35 y/o IVF#1 (ICSI)-- April 2014-- MDL with BCP, 5R, 4 ICSID, 3dt with three embryos, 1 six-day freeze (2BA grade)-- BFN Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 Good luck for your scan tomorrow! It's crazy how so much of it is trial and error. IVF#4 (Dec2013/Jan 2014): Microdose flare+Saizen+testosterone 4 eggs retrieved, all mature and fertilized by ICSI, ET of 1 6-cell embryo an 1 8-cell embryo graded 2 and 3. 0000001169 00000 n Thank you! trouble breathing. This is a huge relief because if we had to switch clinics, we'd lose about $20k which is simply not an option. I have an IVF consult in two weeks and although I've got my questions (mostly from the wise women on this board) I'm trying to get more information on 'protocols'. I stimmed for like 15 days, got 5 eggs, 3 fert with icsi, all disintegrated basically, no blasts. My little one is a success story from MDL! Previous studies comparing E2 priming and leuprolide flare IVF protocols report that E2 priming protocols result in longer cycles and higher total gonadotropin dose with similar oocyte yield, fertilization, and pregnancy rates; though, one report suggests a trend toward higher quality embryos in E2 priming cycles. I just got my calendar today and I'm getting ready to start Lupron. Called the flare, the microdose flare, or the low dose Lupron protocol, this regimen uses the same medications as the Lupron overlap protocol. But I'll let you know if I respond better! Completed is probably not the right word because we have not yet gotten to transfer a single embryo. Then on stimming day 6, they found 18 follies. [Dr. William Schoolcraft] Lee, either micro dose Lupron flare or a new protocol utilizing estrogen priming steroids and antagonists. Any help would be greatly appreciated looking for hope this time around.. Hi everyone, does anyone have any thoughts on which protocol is better for older women and which protocol is best for retrieving good quality, chromosomally normal eggs? The eggs are weaker as we get older and in turn weaker embryos. So now we are dealing with issues on my side and i'm only 26 years old. In 2018 after 4 rounds of ivf I had my daughter. I was diagnosed with high FSH (16). It's a Girl, EDD April 7, 2014. How do they decide? In patients with low egg reserve, this combination may exert . Kate's IF Blog. 2005-2023Everyday Health, Inc., a Ziff Davis company. Lupron Depot is used in men to treat the symptoms of prostate cancer (but does not treat the cancer itself). Good luck on thursday. Infertility doesn't go away after the first positive test. Stimulation Day 1 You will start gonadotropin injections today. (ex. We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. I had blocked tubes and everything else with me and DH was normal. I have a quick question for the veterans. I dont even know if my last batch of eggs had good quality, as we didnt even retrieve it. 0000009266 00000 n This protocol is our favorite for patients with care low ovarian reserve or chancellor who were poor quality after taking BCP. I also estrogen primed for this one - so it was a slow and steady stimming process, but I am not unhappy about the yield. 08/20 - Injection #2 Use of this site is subject to our terms of use and privacy policy. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. Moving forward with CCRM in 2013 Your stories have all made me feel better. Or tips on handling side effects? Then 2X10U Lupron and 2X225U Gonal-F per day for 10 days. 0000000736 00000 n Estrogen Primed Microdose Lupron Flare Protocol The pretreatment phase is a natural cycle in which estrogen is given for 7 days a week after ovulation. Countless BFN(s) Microdose Lupron starts on day 2 of menstrual cycle, and is an injection once in the morning, and again in the evening. 07/23 - Injection #1 This community is sponsored by RESOLVE: The National Infertility Association, an Inspire trusted partner. hi, I did it at age 38. Lower doses like 300 iu follistim didn't work for me. I dont want to keep trying protocols and not succeeding. Advanced Fertility Care Injection Teaching Videos. My first retrieval was an antagonist protocol, and we only got one poor quality embryo (3CB). Previos Post Next Post Stimmed for 12 days and had retrieval on day 14. But I believed we switched because of not getting eggs. This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. You Will Mother. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? For those who have PCOS which IVF Protocol was successful for you? Lupron Depot: May 2013 to August 2013 13R. Good luck! Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. So, we concluded that the microdose flare-up protocol may have a better outcome in poor-responder patients. me 33/DH 36ttc since 10/2008; d/x: mild MFI, stageII endo~~PAIF/SAIF Welcome~~11 IUIs = 1 m/c (7w4d)IVF#1 January 2012 BFN, FET #1 April 2012 BFNSurprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160Stick Frogger Stick! Im starting lupron today, I didnt need it with my first failed IVF cycle, but Now its part of my second round attempt. Lupron Depot is used in women to treat symptoms of endometriosis (overgrowth of uterine lining outside of the uterus) or uterine fibroids. Both my l, Short protocol or long protocol for older women. I did microdose lupron flare protocol with my first IVF. I did microflare lupron after being diagnosed with elevated FSH. Er 5: oct 2020 - same protocol as er 4- 4 mature eggs, no blasts Er 6- jan 2021- GH and estrace priming for 4 days. Only recently. [Sheri] What is DHEA? Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? They said I would, I just completed a second round of IVF/ICSI. No DOR, PCOS or Endometriosis. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. Since TFC opened its doors more than 40 years ago, we have helped our patients deliver 23,000 miracles through IVF, IUI, egg donation, intracytoplasmic sperm injection, and reconstructive fertility surgery. Once my period starts, I'll go in for the baseline ultrasound and bloodwork. 39 year old multiple failed cycles need advice. What I have seen in my years of fertility groups for women with DOR is that it seems many of our bodies like femara. It's not your first rodeo here." Long Lupron protocol. Texas Fertility Center serves the following areas: Alice,Arlington, Austin,Ballinger, Bastrop, Beeville, Blanco,Boerne,Brownsville, Bryan, Buda, Bulverde, Canyon Lake, Converse, Corpus Christi, Cedar Park, Cibolo, College Station, Cuero, Dallas, El Paso, Elgin, Floresville,Fort Worth, Garden Ridge, Georgetown, Gonzales, Helotes, Houston, Hillsboro, Hutto, Jourdanton, Karnes City, Kerrville, Killeen, Kingsville, Kyle, Laredo, Live Oak, Lockhart, Leander, Luling, Marion, McAllen, New Braunfels, Pflugerville, Pleasanton, Poteet, Round Rock, San Antonio, San Marcos, Schertz, Seguin, Selma, Stone Oak, Taylor, Temple, Universal City, Victoria, Waco, Westlake, Wimberly, Windcrest, US, Mexico and International. Your post will be hidden and deleted by moderators. Hi has anyone done a MENOPUR only cycle? He had a vasectomy after his second child. All my cycles were at age 34. How do you recover from a failed IVF? Hope it makes the difference for you! I am 42 and after 1 failed IUI and 1 failed IVF, I am now starting my second round IVF with the lupron flare and ICSI. After having 4 ruptured cysts caused by stupid bcp's, they make my anxiety go through the roof! Attempt #2 is going much better. Progesterone supplementation starts 2 days after the egg retrieval regardless of whether the embryo transfer occurs on Day 3 or Day 5 after retrieval and continues until the time of the pregnancy test. Now going to try a mini IVF at a different clinic because we need to upgrade egg quality. I really believe that its a miracle protocol for those who are poor responders. Did they give you a plan for your cycle yet? Microdose Lupron Flare Protocol. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. Been feeling lonely lately as friends and family are getting pregnant around me (even friends who also struggled with fertility issues), so looking for somewhere else to hopefully find people to connect with. I see a lot of people have taken Lupron. 1Frostie. Stimulation Day 4 Come in for an E2 and LH blood test. Hello, I hope everyone is doing well and hanging in there. He takes my input and works with me. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. The patient is given twice-weekly injections of estradiol valerate (Delestrogen) for a period of 8 days whereupon COS is initiated using a relatively high dosage FSH- (Follistim, Fostimon, Puregon or Gonal F), which is continued along with daily administration of GnRH antagonist until the "hCG "trigger." Devastated! But other doctors have mentioned that it is great for women with DOR. Suite 1200 We did EPP for this last IVF (#4) and it was our best cycle by far. Create an account or log in to participate. I have only ever done 150 and 225 and responded very well. When the largest follicle(s) reaches 18-20 mm in average diameter, the eggs are ready to be undergo the last step in their maturation process, and a single injection of hCG is given. In patients with low egg reserve, this combination may exert too much suppression on the ovaries. The number of daily injections are fewer (4 to 5 days) of antagonists versus 3-4 weeks of agonists) and the length of time to stimulate the follicles to maturity is one or two days shorter, so you may need less total gonadotropins. Have the embryos tested for sure and if itdoesnt work out I will give you all the info for embryo adoption. What my clinic is proposing, however, is starting. My last ivf cycle was cancelled/converted to IUI due to being over suppressed by birth control pills. Group Black's collective includes Essence, The Shade Room and Naturally Curly. In summary, ovarian stimulation is a very complex process. I'm team lupron flair for life. Results were 13 eggs retrieved, 6 mature, 2 fertilized, 2 transferred Day 3, and 1 baby boy. Microdose lupron flare protocol.. Go back for a check on Thursday. Going with a microdose lupron protocol for my 2nd, starting on 11/30. Completely unexplained - sperm count is fine. :) I was a low responder my first round as well, only 1 frozen blast that didn't stick. Ive been priming for transfer for 11 days and Im only at 6.7mm. I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). Austin, TX 78749, 705 Generations Dr, Suite 102 We strive to provide you with a high quality community experience. This is how my current clinic intends to proceed. 1 Call nurse with cd1 Start Microdose (md) Lupron twice daily and continue to take estradiol stopping on cycle day 10 units md Lupron Estradiol 2mg 10 units md Lupron Effect of estrogen priming through luteal phase and stimulation phase in poor. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. He has two girls from a previous marriage. . Wegot completely different results at 43 I got 6 eggs mature eggs & 3 embryos. Primed with BCP. [curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. %PDF-1.4 % Anyone have good success? ", Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN, ET 9/14 2 embies transferred. I am just terrified it will be like my last cycle. Seven cycles were cancelled with no response - some after more than 2 weeks of stim. They also recently found scarred tissue on my lining. 1 single dose LUPRON-at RE office Long time reader, first time poster. SCHEDULE. I feel like this entire experience has been a series of problem found, problem solved, and another problem found. (My clinic requires ICSI and PGS testing for all patients). Our most common protocol utilizes Lupron as a trigger instead of hCG to mature follicles prior to egg collection. (The use of generic Lupron is acceptable.) The LDL protocol was initiated with late luteal lupron (0.25 mg daily). Infertility Support Community in Partnership with RESOLVE. Switch Protocol 2nd Time Around? 2TFR'ed. My cycle "might" be cancelled. I am 41, so getting frustrated now with all these premature ovulation. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. Your diagnosis of For those women whove had more than one ivf cycle, did you change protocol? Please whitelist our site to get all the best deals and offers from our partners. trailer My second we moved from an antagonist to a Lupron stop protocol with PICSI and wound up with 8 embryos, 3 of which were PGS normal. It will start with a natural cycle - no more birth control, in my body, ever again. Team Purple. 0000017159 00000 n Thin Lining - stim protocol - suggestions? MENTS I married at 39 and got pregnant naturally a year later, then miscarried. V-dot patches(20)=estrogen :), I'm confused by all the information out there for women over 40. And offer a ivf protocol. Microdose Lupron Flare Protocol. Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. I tried IVF in may since my follicle count was low I cancelled it. February 2011 Also, if any of you CCRM girls have any words of wisdom, I will take those too! 0000000016 00000 n A Group Leader is a What to Expect community member who has been selected by our staff to help maintain a positive, supportive tone within a group. We ve tried PRPs, neupojin, Hello, I just joined and first post. Next protocol will be micro dose lupron. Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28 Objective: To compare the effect of the GnRH antagonist/letrozole protocol (AL) with the microdose GnRH agonist flare-up (MF) protocol in poor ovarian responders for intracytoplasmic sperm injection (ICSI). Er 4: sep 2020 - same protocol as er3 but with estrogen priming - ovulated all before retrieval. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to I'm gearing up for a 2-month Lupron protocol after 3 failed FETs with PGS normal embryos. Each month is different and that 4 eggs could have been just an off month and not a predictor of your future cycles. Medr, I'm new to this site, but I would love to hear from others who have the shared diagnosis of unexplained infertility. NATURAL EFFORTS: 1st pregnancy and miscarriage in Dec/Jan 2016, successfully treated miscarriage with mis, Hi Ladies, I hate long stims. What did do when you had a cancelled IVF cycle? I did that protocol for 3 IUI's and subsequent IVF and it turns out I'm a low responder with DOR, so that is not the right protocol for me. On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . Decided to cancel on day 9. So I will be on oral estrogen, patches, and injections! DH and I have been TTC for 4.5 years or so: The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. So Im not sure how that changes for you, since you were able to get eggs. Going with a microdose lupron protocol for my 2nd, starting on 11/30. Read Review Toronto Licence Claim Delta. 8Cell 1Grade 2Embies. Changing IVF protocols - any success or thoughts? So if u want to give it one more try isay go for it. They are in a.different country and I cant travel due to covid restrictions. crazy how we have to get creative, huh?? My husband and I started trying in December of 2015, and when coming off of my birth control, I never got my period. It is possible that the ovarian stimulation process on the egg donor would be shorter or longer than that shown above. That said he did the exact same thing back to back and only got 4 and 1 abnormal blast. For how long was the MDL given ? Are you sure you want to block this member? Earnest Letter. Are you sure you want to block this member? <<7e73b458605e884a9eec5f5e9aeedda8>]>> 1Frostie. I am a little concerned that I am supposed to take 300 iu's of Gonal-F. While many studies to evaluate the effectiveness of these additional medications have been conducted, there are unfortunately very few definitive conclusions that have been reached. 3. She has already been prescribing me an aggressive protocol (microdose Lu, So a little bit about me. November IVF Protocol - DOR / LOW AMH / +40. 1. Thoughts on different protocols? my clinic doesnt do growth hormone which Ive always heard good things about it. Any advice is welcome! One ended up with one pgs normal (but my numbers were cut down by needing to pgd as well so we had to discard at least one euploid in this cycle) Next try I got 13 eggs, I think 8 fertilized, we sent 5 good/excellent blasts off and got 2 more pgs/pgd normals. fainting. We respect everyones right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expects Terms of Use. I had 16 eggs, 10 mature and all 10 fertilized. Hello All, Finally some (tough) answers. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . Has anyone used this protocol and had any success? This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. FET. I'm a bit concerned about too much too quickly. So- that's what's going on. 43 &37 eggs?! Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . I am not familiar with it, but I will definitely some research. With IVF#2, I got 16 eggs, 15 of which were mature. The use of Lupron to trigger egg maturation over the past 4-5 years has gained popularity when given in a single higher dose (4mg) with aggressive supplementation of estrogen and progesterone following the egg retrieval. Long awaited FET on 9/3. I took BCP for 3 weeks. I didn't respondall thatwell to my Follistim-Ganirelex protocol during IVF #1 and my RE told me today he's going to try this for #2. Non left to freeze --> BFN IVF#5 (April/May 2014): Antagonist Estrogen Priming -Cornell Protocol (Clomid+ Menopur+Gonal F + Orgalutran) Now.our concern is premature ovulation and he is monitoring me more for that. Im 42, have DOR and my AMH is .90. With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. But ever since then, despite having a lot of embryos, we were never able to repeat this success. Note that once you confirm, this action cannot be undone. How many days do you take menopur for IVF? I do believe the MIcrodose Flare P is the way to go for women older with fewer eggs. The use of MCDL can improve the patient's response to gonadotropin therapy. Thanks. 0000001853 00000 n Hi. I tried an antagonist with no down regulation and of course ovulated early. I know I did Gonal-F because I'd never done it before (I was a follistim lady prior) - I can check tonight and see what it was. Austin, Texas 78731, 16040 Park Valley Drive Building 1, Ste 201 fast or irregular breathing. Final u/s showed 5 follicles, stimmed for 2 weeks but ovulated all during retrieval. I'm starting IVF#3 on November 14th. If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. I'm 42 y/o and had my 2nd egg retrieval on 4/16. Apparently we waited too long ? Thanks! I have DOR (My AMH was 0.38 and 0.27 in 2016, but somehow it increased to 1.36 in Jan 2017). I'm looking for some insight on the microdose lupron protocol. %%EOF Doc consult at the end of this month. 3 failed IUI's 13R. It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. Did anyone have success with MDL high dose protocol for DOR and over 40? It was my first IVF after a failed IUI. TTC 2 years. Transfered a blast and early blast and froze one. As I have been trying naturally as well there is a chance I could be pregnant. Twins with an EDD of 8/15/14! 0 With IVF#2, I got 16 eggs, 15 of which were mature. Hi all, I'm about to start a ton of supplements my nurse suggested to me. Because my follicle growth was so dysfunctional during my first round my doctor has decided to try a microdose lupron flare protocol starting with 5 weeks of birth control which ends on Monday. I wont be using birth control, just starting lupron a week after ovulation. I will never know if they were normal or not. 28 years old, first IVF cycle cancelled?! He is suggesting microdose lupron flare with GH. The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to support the lining. Well, if any of you can share tips, advice, experiencesI would greatly appreciate it! Woot woot!! We started our second cycle on Friday (7th). Hopefully they know what they're doing! (week of) 09/27 - Transfer Foll, and Meno. With IVF#2, we did MDL. What now - IUI, Adoption, Donor Eggs or Donor Embryos, Retire Early?! Estrogen primed microdose lupron flare protocol karela After 5-6 days of stimulation an antagonist is added to prevent ovulation until the day of. Please whitelist our site to get all the best deals and offers from our partners. You start today right?!? We retrieved 8 eggs and 8 were fertilized. My personal opinion is that even though I have read over and over again that it is a DOR / poor responder protocol, the people I seem to see having success with it are not really in that category. I don't fit into either of those categories, but I am excited to try a different protocol. Lazer T, Liu A, et al. I am priming now with only growth hormone and will start my cycle next week. I badly want to be a mom. it helps prevent ovulation - 1/8 tablet or 1/4 tablet, inserted vaginally, overnight (and i use a special silicone plug, AND, /the inner plunger from a tampon applicator/, to push the plug deeper or else it slides out if you need to use the loo, during the night. I did my first IVF at 39 got 3 embryos with one pgta normal.

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